Rapamycin is one of the most effective drugs in modern medicine with a wide range of applications. Isolated in 1972, the drug was first used as an anti-fungal agent. The drug was later discovered to possess immunosuppressive and anti-proliferative properties. This discovery forced physicians to quit using the drug as an anti-fungal agent but to apply it to more serious health issues.
Rapamycin has since been used to prevent organ transplant rejection, treat rare lung disease, and used as a cancer drug.
Mikhail Blagosklonny, a reputable professor of Oncology at the Rosewell Park Cancer Institute, who has carried out countless research on the subject of aging by virtue of his position as the Editor-in-chief of Oncotarget, has advocated that Rapamycin is used for extending the lifespan of human beings. Read more about Mikhail on Crunchbase.
Below is a list of some of the medical application of the wonder drug Rapamycin;
- Immunosuppressive properties:
When the body receives a new organ its first reaction will be to reject such organ. if this happens, the transplantation fails. Therefore, physicians use anti-rejection drugs or immunosuppressive drugs to allow the body receive the new organ. These anti-rejection drugs, however, will have an adverse effect on the kidney in the long run. Rapamycin, on the other hand, is an immunosuppressive drug but which shows very low toxicity towards the kidneys.
- Treatment of Lymphangioleiomyomatosis
Lymphangioleiomyomatosis is a rare lung disease which is known to affect women within the childbearing bracket. Rapamycin is the only drug approved for the treating of this disease.
- Treatment of cancer:
Rapamycin possess anti-proliferative properties thereby making it a very effective drug for treating cancer. It helps enhance the immune system’s response to cancerous cells. It also promotes tumor regression.
Other areas where Rapamycin has found use within the medical field includes; treating patients with hemolytic-uremic syndrome, Coronary Stent Coating, treating Tuberous Sclerosis Complex, and treating facial angiofibroma.
Research is in progress on how Rapamycin can be used in the following areas; increasing longevity in man, treatment of Alzheimer disease, muscular dystrophy, Systemic Lupus Erythematosus
By virtue of their economic standing or societal background, many people are deprived access to the best possible medical treatment for their ailments. Mikhail Blagosklonny is one individual who wishes to see this change. He is a professor, a researcher, and philanthropist, who is particularly interested in the field of medical research and has placed emphasis on the study of the relationship between cancer and aging. Mikhail wishes to understand the connection between the two and also to ascertain why cancer is more common in older people above a certain age.
Mikhail Blagosklonny’s life and work will continue to be an inspiration to his peers and students who wish to expand on his research in the nearest future. His research has been useful and will continue to play a crucial role in the oncology field.
His unique research focus has drawn the attention of many within the medical field. His goal is to find a way to treat cancer that will not be excruciating or as expensive as what is obtainable. He hopes to develop a more effective means of treating cancer. He hopes to find a way to eliminate cancer cells without having to destroy the normal cells that will be very useful for recovery. Visit classroomvoices.org to read more about Mikhail.